3-Dimethylaminopropylamine DMAPA CAS 109-55-7
3-Dimethylaminopropylamine (abbreviated as DMAPA), identified by CAS number 109-55-7 and IUPAC name N’,N’-dimethylpropane-1,3-diamine, is a high-reactivity aliphatic diamine characterized by a propylene backbone functionalized with both primary (-NH2) and tertiary (-N(CH3)2) amine groups . With a molecular formula of C5H14N2 and a molecular weight of 102.18 g/mol, this compound presents as a colorless to pale yellow transparent liquid with a distinct ammoniacal odor . Its dual amine functionality—combining nucleophilic reactivity (primary amine) and catalytic activity (tertiary amine)—paired with complete miscibility in water, alcohols, and aromatic solvents (toluene, xylene) makes it an irreplaceable intermediate in high-value industrial processes .
At Nantong Lanpu Chemical, we specialize in the synthesis of pharmaceutical-grade 3-Dimethylaminopropylamine, adhering to GHS regulatory frameworks. Our proprietary distillation process achieves ultra-low impurity levels, ensuring batch-to-batch consistency that meets the stringent requirements of surfactant, pharmaceutical, and polymer industries across 40+ countries.
Lanpu-DMAPA Technical Data Sheet
| Parameter | Industry Specification | Reference | Nantong Lanpu Standard |
| Chemical Identity | 3-Dimethylaminopropylamine; DMAPA;N’,N’-Dimethylpropane-1,3-diamine | – | Fully Compliant |
| EC Number | 203-680-9 | – | 203-680-9 |
| Appearance | Colorless to pale yellow liquid | – | Colorless transparent liquid (APHA ≤20) |
| Purity (GC) | ≥99.0% | – | ≥99.5% |
| Moisture Content | ≤0.3% | – | ≤0.2% |
| UN Number | UN 2734 | – | UN 2734 |
| Hazard Class | 3 (Flammable Liquid) / 8 (Corrosive) | – | 3/8, PG 2 |
Industrial Applications of 3-Dimethylaminopropylamine
The synergistic effect of primary and tertiary amine groups in 3-Dimethylaminopropylamine drives its dominance in high-growth industrial sectors. Below are its core applications, optimized by Nantong Lanpu Chemical’s premium formulation:
- Surfactant Synthesis for Personal Care
DMAPA is the primary intermediate for manufacturing alkylamidopropyl betaines—mild, biodegradable surfactants that balance foaming, cleansing, and conditioning properties . These surfactants are integral to premium shampoos, body washes, and facial cleansers, as they avoid skin irritation (irritation index maintaining stable foam even in hard water (300ppm CaCO₃) . Nantong Lanpu’s low-moisture DMAPA ensures consistent amidation reactions, producing surfactants with uniform chain length distribution—critical for baby care and sensitive-skin products.
- Epoxy Resin Curing & Polymer Catalysis
As an epoxy curing agent, DMAPA enables rapid ambient-temperature curing (25°C/24h) due to its highly reactive tertiary amine group, delivering cured resins with a tensile strength of 65–75 MPa and elongation at break of 4–6% . It also acts as a high-efficiency catalyst for polyurethane (PU) foam production, reducing curing time by 30% while lowering VOC emissions to g/L—compliant with EU REACH Annex XVII . Our 99.5% pure DMAPA eliminates curing defects in high-precision composites used in automotive lightweighting.
- Pharmaceutical & Agrochemical Intermediates
In pharmaceutical synthesis, DMAPA serves as a deprotection agent in solid-phase peptide synthesis (SPPS), efficiently cleaving Fmoc groups from amino acids with >99% yield . It is also a key intermediate for synthesizing antihistamines and cardiovascular drugs, where impurity control directly impacts API bioavailability. In agrochemicals, DMAPA derivatives act as systemic fungicides, targeting fungal cell wall synthesis with minimal environmental persistence. Nantong Lanpu’s DMAPA complies with FDA 21 CFR Part 178 and EMA ICH Q9 guidelines for pharmaceutical use.
- Water Treatment & Metalworking Fluids
DMAPA forms chelating agents that sequester heavy metals (Fe³+, Cu²+) and inhibit scale formation in industrial boilers, reducing maintenance costs by 40% compared to traditional inhibitors . In metalworking, it functions as a corrosion inhibitor in water-miscible coolants, forming a protective film on steel surfaces (corrosion rate mm/year) . Our product’s low chloride content (<50ppm) prevents pitting corrosion in high-pressure hydraulic systems.
- Dyes, Adhesives & Textile Auxiliaries
DMAPA is a critical building block for reactive dyes and acid dyes, enhancing color fastness to washing (ISO 105-C06: Grade 4–5) and light (ISO 105-B02: Grade 5) . In adhesives, it improves bonding strength to polyolefins by 25% when used as a coupling agent . In textiles, it modifies polyester fibers to enhance dye uptake, reducing dye consumption by 20% . Nantong Lanpu’s DMAPA supports sustainable manufacturing through these efficiency gains.
Packaging & Storage | Nantong Lanpu Chemical
We provide globally compliant packaging solutions tailored to preserve DMAPA’s reactivity and ensure safe logistics:
Packaging Specifications
- Bulk Supply: 165kg irondrums or as required
All packaging is UN-certified for Class 3/8 hazardous materials, featuring bilingual labels (English/Chinese) with CAS number, hazard symbols (flammable, corrosive), and emergency contact information. Nantong Lanpu’s drums undergo leak-testing to meet IMDG and DOT standards for international shipping.
Storage Guidelines
- Environment: Store in a cool (≤30°C), explosion-proof warehouse with mechanical ventilation (air exchange rate ≥6 times/hour) . Avoid direct sunlight to prevent thermal decomposition.
- Containment: Maintain tight seals to prevent vapor release—DMAPA vapor forms explosive mixtures with air at concentrations of 1.5–12% (v/v) .
- Segregation: Separate from oxidizers (hydrogen peroxide, potassium permanganate), strong acids (sulfuric acid), and foodstuffs using dedicated storage racks (minimum distance: 1m) .
- Shelf Life: 1years when stored in unopened original packaging; conduct GC purity testing before use if stored beyond this period .
Each shipment includes a COA with impurity profiles (GC-MS verified) and a GHS-compliant SDS. Our logistics team coordinates temperature-controlled transport for bulk orders to prevent quality degradation.
Why Choose Nantong Lanpu Chemical?
As a leading supplier of 3-Dimethylaminopropylamine (CAS 109-55-7), we deliver competitive advantages:
- Ultra-High Purity: 99.5% minimum purity (GC-tested) with ≤0.2% moisture.
- Global Compliance: FDA-compliant, and ISO 14001-certified for sustainable production.
- Technical Expertise: Our R&D team provides custom dosage and formulation support for specialized applications (e.g., low-irritation surfactants, fast-cure epoxies).
- Reliable Supply: 5,000 MT/year production capacity with 99% on-time delivery rate to US, and Southeast Asian markets.
Contact us today for a personalized quote, to request a sample, or to access our interactive SDS database for 3-Dimethylaminopropylamine.
To buy 3-Dimethylaminopropylamine DMAPA CAS 109-55-7 from factory in China, Lanpu Chemical offers competitive price with full product support, including specifications, MSDS, TDS, and COA. For factory-price 3-Dimethylaminopropylamine, contact sonia@lanpuchemical.com.
FAQ：
- How does 3-Dimethylaminopropylamine (CAS 109-55-7) perform in surfactant synthesis, and why does purity matter?
Answer: 3-Dimethylaminopropylamine (DMAPA) is the irreplaceable core intermediate for alkylamidopropyl betaines—mild, biodegradable surfactants dominating premium personal care products . Its primary amine group undergoes amidation with fatty acids/methyl esters, while the tertiary amine group enables subsequent quaternization to form betaines, balancing foaming (foam height ≥180mm in 30s), cleansing, and conditioning properties. These surfactants maintain stable foam even in hard water (300ppm CaCO₃) and have an irritation index <0.5, making them ideal for baby care and sensitive-skin formulations.
- What safety precautions are required when handling 3-Dimethylaminopropylamine?
Answer: 3-Dimethylaminopropylamine (CAS 109-55-7) is classified as flammable (H226, flash point 36°C) and corrosive (H314, pH 12.2), posing dual risks requiring strict controls . Routine Handling Protocols: PPE Requirements: Wear ASTM F1001-18 chemical suits with taped seams, 0.2mm nitrile gloves (ASTM D6319, 4-hour breakthrough time), and full-face respirators with ABEK filters .
3.How does 3-Dimethylaminopropylamine compare to DEAPA for epoxy curing, and which to choose?
Answer: 3-Dimethylaminopropylamine (DMAPA) and 3-Diethylaminopropylamine (DEAPA) are both dual-amine epoxy curing agents, but their structural differences drive distinct use cases:
Choose DMAPA if:you need rapid ambient curing (e.g., assembly-line epoxy adhesives);targeting lightweight automotive parts (cured resin tensile strength 65–75 MPa);reducing energy consumption (no heating required).
